Antiproliferative Factor Signaling and Interstitial Cystitis/Painful Bladder Syndrome
نویسندگان
چکیده
منابع مشابه
Antiproliferative Factor Signaling and Interstitial Cystitis/Painful Bladder Syndrome
A unique glycopeptide, antiproliferative factor (APF), has been suggested as a urinary biomarker and potential mediator of long-term bladder disorder Interstitial Cystitis/Painful Bladder Syndrome. There is no known cause for this disease. Several mechanistic approaches have been employed to address the underlying mechanism whereby APF regulates cellular responses in the bladder epithelium. A s...
متن کاملPotential Use of Antiproliferative Factor as a Targeting Therapy in Painful Bladder Syndrome/Interstitial Cystitis
Painful bladder syndrome/interstitial cystitis (PBS/IC) encompasses a major portion of the “painful bladder” disease complex. “Painful bladder disorders” comprise a large group of patients with bladder and/or urethral and/or pelvic pain, irritative voiding symptoms (urgency, frequency, nocturia, and dysuria), and sterile urine cultures. Painful bladder conditions with well-established causes in...
متن کاملBladder Pain Syndrome/Interstitial cystitis:
Background BPS/IC is a chronic syndrome with bladder pain, divided into two main types: one with so called Hunner`s lesions (classic type) and one without (nonulcer type). In the recently presented ESSIC classification system the classic type, in focus of the present work, has the designation Type 3C BPS/IC. Symptoms are characterized by bladder pain, urgency, frequency and nocturia. The aetiol...
متن کاملInterstitial cystitis/painful bladder syndrome.
Interstitial cystitis/painful bladder syndrome affects more than 1 million persons in the United States, but the cause remains unknown. Most patients with interstitial cystitis/painful bladder syndrome are women with symptoms of suprapubic pelvic and/or genital area pain, dyspareunia, urinary urgency and frequency, and nocturia. It is important to exclude other conditions such as infections. Te...
متن کاملPainful bladder syndrome/interstitial cystitis.
Painful bladder syndrome (PBS) is the term used to refer to a chronic symptom complex of urinary frequency and bladder 'pressure', discomfort or pain in the absence of any other reasonable cause for these symptoms (such as infection). Interstitial cystitis (IC) is the established term used by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) consensus workshop for whi...
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ژورنال
عنوان ژورنال: International Neurourology Journal
سال: 2011
ISSN: 2093-4777,2093-6931
DOI: 10.5213/inj.2011.15.4.184